PAN-CANCER STRUCTUROME REVEALS OVERREPRESENTATION OF BETA SANDWICHES AND UNDERREPRESENTATION OF ALPHA HELICAL DOMAINS

Pan-cancer structurome reveals overrepresentation of beta sandwiches and underrepresentation of alpha helical domains

Abstract The recent progress in the prediction of protein structures marked Stock a historical milestone.AlphaFold predicted 200 million protein models with an accuracy comparable to experimental methods.Protein structures are widely used to understand evolution and to identify potential drug targets for the treatment of various diseases, including

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Comparative study of expandable cage with integrated plate versus non expandable cage in cervical spine corpectomies

Background: The use of expandable cages in cervical spine has gained popularity over the last decade.They have been used in dorsal spine since long but were rarely used in cervical spine due to their high cost.Now, with more insight into their mechanics, many advantages have been noted over the fixed cages along with similar efficacy and with no ad

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Cataract surgery complications in a patient with brittle cornea syndrome and Ehlers-Danlos syndrome type six: A case report

Purpose: This case report delineates the intricacies and challenges encountered in cataract surgery in Stock Ehlers-Danlos syndrome type VI presenting with advanced Keratoglobus (KG), severe cataract and brittle cornea.Observations: Despite meticulous planning and intraoperative precautions, including phacoemulsification with reduced intraocular pr

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